FORMULATION AND EVALUATION OF ANTIMICROBIAL POTENTIAL OF HERBAL CREAM CONTAINING MORINGA LEAF AND POMEGRANATE PEEL

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Arati hattimare; Mayur patle; Vijayashree Patle; Dr. T .P. Nimbekar

FORMULATION AND EVALUATION OF ANTIMICROBIAL POTENTIAL OF HERBAL CREAM CONTAINING MORINGA LEAF AND POMEGRANATE PEEL

Authors: Arati hattimare, Mayur patle, Vijayashree Patle, Dr. T .P. Nimbekar

Unique Paper ID: 176733
Volume: 11
Issue: 11
PageNo: 7554-7560

Keywords: secondary metabolites anti-microbial anti-inflammatory anti-oxidant anti-aging organoleptic characteristics inhibition zones.

Abstract:
Moringa oleifera and pomegranate peel is considered a versatile plant. It has been shown that antimicrobial properties, anti-inflammatory, anti-oxidant properties exist exist in leaves, stem bark, root bark, cotyledon seeds, and seed coats. These antimicrobial properties are believed to be due to secondary metabolites such as alkaloids, flavonoids, glycosides, terpenoids, and sterols. Acne is a common skin condition`belived to be caused by the build-up of dead skin cells, bacteria, and dried sebum that blocks the hairs follicles in the skin. This study aims to evaluate the anti-microbial activity of hydroalcoholic extract of moringa oleifera leaves and pomegranate peel with concentration of 5%, 10%,15% and 20% formulated into topical cream preparations against Staphylococus epidermidis. The moringa leaves powder were assemble in soxhlet apparatus for extraction for 24 hrs in 70% ethanol and pomegranate peel powder were assemble in soxhlet apparatus for extraction for 48 hrs in 50% ethanol. Four extract concentration were prepared: 5%, 10%, 15% and 20%. The cream was physically evaluated for its organoleptic characteristics, homogeneity, pH, and adhesion. Also the anti- microbial activity tests of moringa leaves and pomegranate peel extracts revealed that formulas 1,2,3 and 4 had inhibition zones between 6.12mm, 7.98 mm, and 8.35 mm, respectively. In conclusion, the formulations containing 5%, 10%, 15% and 20% moringa leaf and pomegranate peel extract showed anti- microbial activity against the test organism and normal range for organoleptic, homogeneity and viscocity test, pH and adhesion tests.

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ISSN: 2349-6002
Volume: 11
Issue: 11
PageNo: 7554-7560

FORMULATION AND EVALUATION OF ANTIMICROBIAL POTENTIAL OF HERBAL CREAM CONTAINING MORINGA LEAF AND POMEGRANATE PEEL

Available:https://ijirt.org/article?manuscript=176733

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

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