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Formulation Strategy and Optimization of Betahistine-Encapsulated Microspheres

  • Unique Paper ID: 178501
  • Volume: 11
  • Issue: 12
  • PageNo: 3441-3443
  • Abstract:
  • Betahistine, a histamine analog, is widely used for the treatment of vertigo, tinnitus, and Meniere’s disease—conditions associated with vestibular disorders and inner ear dysfunction. Despite its therapeutic potential, Betahistine’s clinical effectiveness is limited due to its short half-life, rapid systemic clearance, and low oral bioavailability. To address these challenges, polymeric microspheres—particularly those formulated with biodegradable materials such as poly(lactic-co-glycolic acid) (PLGA) and chitosan—offer promising avenues for controlled and sustained drug release. The present study focuses on the formulation and optimization of Betahistine-loaded microspheres, with the aim of developing a scalable and commercially viable drug delivery system.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 12
  • PageNo: 3441-3443

Formulation Strategy and Optimization of Betahistine-Encapsulated Microspheres

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8.01 (Year 2024)
UGC Approved
Journal no 47859

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