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@article{179401,
        author = {Sagar Sahu and Kartavya Patel and Gunjan Kalyani},
        title = {Chemogenomics: An Evolving Stratagem for Swift Target and Drug Discovery},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {6201-6212},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=179401},
        abstract = {Chemogenomics aims to systematically
understand the relationships between chemical
compounds and their biological activities across a range
of targets, often within entire protein families. This
approach leverages the wealth of genomic information
to identify novel drug targets, by observing how
compounds affect various biological systems and
linking these effects to specific genes and proteins.
Discovery of new drugs by screening targeted libraries
of compounds against families of related drug targets.
Also to understand drug mechanisms of actions by
determining which proteins a compound interacts with
to produce its observed effects. It also predicts potential
side effects by identifying off-target interactions that
might lead to adverse reactions. And at last, to develop
more selective drugs by understanding the subtle
differences in compound interactions across related
targets. Modern genomics technologies, such as highthroughput sequencing, microarrays, and CRISPRbased gene editing, play a crucial role in
chemogenomics by enabling researchers to study the
effects of compounds on a large scale and with high
precision. In essence, chemogenomics bridges the gap
between the chemical world of drug-like molecules and
the biological world of genes and proteins, offering a
powerful approach to drug discovery and
understanding biological systems.},
        keywords = {Chemogenomics, Drug targets, Highthroughput sequencing, CRISPR, Drug discovery.},
        month = {May},
        }