A VALIDATED UV- VISIBLE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ZOLPIDEM TARTRATE AND SIBUTRAMINE HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM

  • Unique Paper ID: 156120
  • PageNo: 848-865
  • Abstract:
  • The proposed methods are simple, sensitive, rapid, reproducible,with good precision and accuracy needs no heating, colour development is instantaneous, color developed is stable for more than 24hours. Further, the controlling of experimental conditions is minimum. Various Spectrophotometric methods are available in the literature for estimation of drugs by ion association complex method. No method is reported in the literature for estimation of the selected drugs by using proposed dyes. The selectivity and sensitivity of the spectrophotometric methods depends only on the nature of chemical reactions involved in color development and not on the sophistications of the experiment. UV and Visible spectrophotometric methods are highly versatile, sensitive. Hence it is recommended to use proposed dyes for the estimation of the selected drugs by spectrophotometry. These methods can be used for routine determination of ZLPT and SBT in bulk samples and in pharmaceutical formulations.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{156120,
        author = {Kumaraswamy.Gandla and Sravanthi Gandu and Juluri Bhasker and Pingili. Kavitha},
        title = {A VALIDATED UV- VISIBLE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ZOLPIDEM TARTRATE AND SIBUTRAMINE HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {9},
        number = {2},
        pages = {848-865},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=156120},
        abstract = {The proposed methods are simple, sensitive, rapid, reproducible,with good precision and accuracy  needs no heating, colour development is instantaneous, color developed is stable for more than 24hours. Further, the controlling of experimental conditions is minimum. Various Spectrophotometric methods are available in the literature for estimation of drugs by ion association complex method. No method is reported in the literature for estimation of the selected drugs by using proposed dyes. The selectivity and sensitivity of the spectrophotometric methods depends only on the nature of chemical reactions involved in color development and not on the sophistications of the experiment. UV and Visible spectrophotometric methods are highly versatile, sensitive. Hence it is recommended to use proposed dyes for the estimation of the selected drugs by spectrophotometry. These methods can be used for routine determination of ZLPT and SBT in bulk samples and in pharmaceutical formulations.},
        keywords = {UV-Visible Spectrocopic Method; Zolpidem Tartrate; Sibutramine HCL;0.1 N HCl},
        month = {},
        }

Cite This Article

Kumaraswamy.Gandla, , & Gandu, S., & Bhasker, J., & Kavitha, P. (). A VALIDATED UV- VISIBLE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ZOLPIDEM TARTRATE AND SIBUTRAMINE HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM. International Journal of Innovative Research in Technology (IJIRT), 9(2), 848–865.

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