METHOD DEVELOPMENT AND VALIDATION OF FINERENONE BY RP-HPLC METHOD

  • Unique Paper ID: 166111
  • Volume: 11
  • Issue: 2
  • PageNo: 751-761
  • Abstract:
  • A simple, sensitive, accurate, rapid and specific RP-Hplc method was developed for estimation and validation of Finerenone in pure drug and tablet dosage form. chromatographic separation was achieved on an symmetry ODS C analytical column using mobile phase composition of methanol and phosphate buffer in ratio of 35:65% that was set at the flow rate of 1.0 ul/min with detection of 235 nm. The presentation of method was validated according to present ICH guideline for accuracy precision and robustness, linearity, limit of quantification, limit of detection linearity.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{166111,
        author = {Vijay Metkari and Dr. Swati Deshmukh and Miss. Vanita Gade},
        title = {METHOD DEVELOPMENT AND VALIDATION OF FINERENONE BY RP-HPLC METHOD},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {2},
        pages = {751-761},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=166111},
        abstract = {A simple, sensitive, accurate, rapid and specific RP-Hplc method was developed for estimation and validation of Finerenone in pure drug and tablet dosage form.   chromatographic separation was achieved on an symmetry ODS C analytical column using mobile phase composition of methanol and phosphate buffer in ratio of 35:65% that was set at the flow rate of 1.0 ul/min with detection of 235 nm. The presentation of method was validated according to present ICH guideline for accuracy precision and robustness, linearity, limit of quantification, limit of detection linearity.},
        keywords = {Finerenone, RP-HPLC, Method development, Accuracy, Precision.},
        month = {July},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 2
  • PageNo: 751-761

METHOD DEVELOPMENT AND VALIDATION OF FINERENONE BY RP-HPLC METHOD

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