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@article{169608,
author = {Dr.Devendra M. Bahiram and Dr Neelam S Valhekar and Dr Priyadarshan M Joglekar},
title = {Toxicology of Datura —Ayurvedic Review},
journal = {International Journal of Innovative Research in Technology},
year = {2024},
volume = {11},
number = {6},
pages = {1303-1306},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=169608},
abstract = {Dhatura, a genus of medicinal herb from the Solanaceae family, is credited with toxic as well as medicinal properties. The different plant parts of Dhatura sp., mainly D. stramonium L., commonly known as Dhatura or Jimson Weed, exhibit potent analgesic, antiviral, anti-diarrheal, and anti-inflammatory activities, owing to the wide range of bioactive constituents. With these pharmacological activities, D. stramonium is potentially used to treat numerous human diseases, including ulcers, inflammation, wounds, rheumatism, gout, bruises and swellings, sciatica, fever, toothache, asthma, and bronchitis. The primary phytochemicals investigation on plant extract of Dhatura showed alkaloids, carbohydrates, cardiac glycosides, tannins, flavonoids, amino acids, and phenolic compounds. It also contains toxic tropane alkaloids, including atropine, scopolamine, and hyoscamine. Although some studies on D. stramonium have reported potential pharmacological effects, information about the toxicity remains almost uncertain. Moreover, the frequent abuse of D. stramonium for recreational purposes has led to toxic syndromes. Therefore, it becomes necessary to be aware of the toxic aspects and the potential risks accompanying its use. The present review aims to summarize the phytochemical composition and pharmacological and toxicological aspects of the plant Dhatura.},
keywords = {Dhatura stramonium, alkaloids, atropine, cardiac glycosides, hyoscamine, Ayurveda},
month = {November},
}
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