Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{170066,
        author = {Nilesh P. Musmade and Dr. V. M. Satpute and Mr. Ghodke S. R.},
        title = {Zidovudine-Loaded Nanoparticles: A Review Of Novel Formulation Strategies For HIV Therapy},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {3075-3079},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170066},
        abstract = {The paper reviews the recent advancements in the formulation of Zidovudine (AZT) using nanoparticles for enhanced delivery in HIV therapy. Zidovudine, a key antiretroviral agent, has limitations in terms of bioavailability, toxicity, and drug resistance. Nanoparticles offer a promising approach to overcome these limitations by improving the pharmacokinetics, targeting specific tissues, and minimizing adverse effects. This review discusses different nanoparticle systems, including lipid nanoparticles, polymeric nanoparticles, and solid lipid nanoparticles, as well as their potential for enhancing the therapeutic efficacy of Zidovudine. Additionally, the paper covers recent progress in nanoparticle surface modifications, controlled-release formulations, and combination therapies aimed at improving patient outcomes in HIV management.},
        keywords = {Zidovudine, Antiretroviral treatment, Limitations of therapy, Nanoparticle drug delivery.},
        month = {November},
        }