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@article{170185, author = {Divya Jagtap and Neha B. Gaikwad and Ankita B. Barhate and Anuja G. Baswekar and Anishka R. Sonawane}, title = {The Science Of Hair Greying: Mechanisms, Causes, And Remedies}, journal = {International Journal of Innovative Research in Technology}, year = {2024}, volume = {11}, number = {6}, pages = {3687-3695}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=170185}, abstract = {As healthy hair is a sign of general well-being and youth. As we can see, the current lifestyle is strongly affecting the pigmentation of hair and causing premature hair greying. As the obvious sign of premature hair greying is loss of pigment production and deposition within. Melanogenesis, a process in which melanin is produced and the enzymes involved are tyrosinase and L-3,4-dihydrooxyphenylalanine(DOPA)-oxidase. The melanogenesis occurs in anagen phase of hair cycle while in catagen phase hair follicle detaches from blood supply and in telogen phase the hair follicle is inactive i.e. in resting phase. A recent study suggests that bulge melanocytes stem cells (MSC) are the key cell for hair greying. The main cause of the hair greying is oxidative stress in hair follicle. There are many marketed products (synthetic and herbal) for the treatment of hair greying. It was suggested to use herbal products than synthetic products as herbal products is more beneficial than synthetic products.}, keywords = {Hair, Hair cycle, Hair greying, Hair follicle, Oxidative stress, DOPA, Anti-greying products.}, month = {December}, }
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