NEPHROTOXICITY A REVIEW ON MECHANISM PREVENTION AND EMERGING BIOMARKERS FOR DRUG INDUCED NEPHROTOXICITY

  • Unique Paper ID: 170570
  • PageNo: 877-882
  • Abstract:
  • Nephrotoxicity can cause kidney injury by various types of drugs and chemicals. Drug-induced nephrotoxicity must be identified early and prevented. The aim of this review is to present a summary of the mechanisms of drug-induced nephrotoxicity and identification of new biomarkers. Knowledge regarding nephrotoxicity, including the findings that serum creatinine and blood urea are frequently used indicators of nephrotoxicity. We also examine novel biomarkers with improved sensitivity and specificity, such as proteinuria, kidney injury molecule-1 (KIM-1), and neutrophil gelatinase-associated lipocalin (NGAL), to identify nephrotoxicity. Additionally, we understand the strategies for avoiding drug-induced nephrotoxicity. In addition to offering a comprehensive overview of the current state of knowledge in this field, this review emphasizes the significance of early detection and prevention of drug-induced nephrotoxicity.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{170570,
        author = {Divya Katoch and Raibarinder Singh and Taniya and Tamanna and Saurav Anand},
        title = {NEPHROTOXICITY A REVIEW ON MECHANISM PREVENTION AND EMERGING BIOMARKERS FOR DRUG INDUCED NEPHROTOXICITY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {877-882},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170570},
        abstract = {Nephrotoxicity can cause kidney injury by various types of drugs and chemicals. Drug-induced nephrotoxicity must be identified early and prevented. The aim of this review is to present a summary of the mechanisms of drug-induced nephrotoxicity and identification of new biomarkers. Knowledge regarding nephrotoxicity, including the findings that serum creatinine and blood urea are frequently used indicators of nephrotoxicity. We also examine novel biomarkers with improved sensitivity and specificity, such as proteinuria, kidney injury molecule-1 (KIM-1), and neutrophil gelatinase-associated lipocalin (NGAL), to identify nephrotoxicity. Additionally, we understand the strategies for avoiding drug-induced nephrotoxicity. In addition to offering a comprehensive overview of the current state of knowledge in this field, this review emphasizes the significance of early detection and prevention of drug-induced nephrotoxicity.},
        keywords = {Nephrotoxicity, Glomerulonephritis, tubular cell toxicity, crystal nephropathy, thrombotic microangiopathy, Neutrophil gelatinase associated lipocalin (NGAL), Kidney injury molecule-1(KIM-1)},
        month = {December},
        }

Cite This Article

Katoch, D., & Singh, R., & Taniya, , & Tamanna, , & Anand, S. (2024). NEPHROTOXICITY A REVIEW ON MECHANISM PREVENTION AND EMERGING BIOMARKERS FOR DRUG INDUCED NEPHROTOXICITY. International Journal of Innovative Research in Technology (IJIRT), 11(7), 877–882.

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