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@article{170597,
        author = {Samina Kumari and Supriya Kashyap and Nazia Khursheed and Rahul and Mohammad Suhaib Dar},
        title = {PHYTOCHEMICALS AND NEUTRACEUTICALS PROMISSING THERAPEUTICS FOR DRUG-INDUCED NEPHROTOXICITY.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {3592-3597},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170597},
        abstract = {An important health concern that can occur as a side effect of several drugs is drug-induced nephrotoxicity. The main symptom of this illnessis hypovolemia, which might affect kidney function by constricting the afferent arteriole. Nephrotoxicity is more common in some populations, including those with heart failure, sepsis, and chronic dehydration. This is due to drugs like NSAIDs,cyclosporines and chemotherapeutic agents like cisplatin. These medications harm people via a number of pathways, such as inflammation, mitochondrial damage, and oxidative stress (Reactive oxygen species). Nutraceuticals and phytochemicals have demonstrated promise in reducingnephrotoxicity. Green tea, curcumin and flavonoids are examples of medicinal plants having anti-inflammatory and antioxidant qualities that have shown nephroprotective effects in preclinical research.In diseases like acute kidney injuryresveratrol and naringeninfor instance have been demonstrated to decrease oxidative damage and enhance renal function. The anti-inflammatory and antioxidant properties of nutraceuticals, such as omega-3 fatty acids, have also made them promising therapeutic agents for preserving renal function. This review looks at how drugs cause nephrotoxicity, how phytochemicals and nutraceuticals protect the kidneys and how they might be used therapeutically to stop drug-induced renal damage.},
        keywords = {Drug-induced nephrotoxicity, Phytochemicals, Oxidative stress, Nephroprotective, Resveratrol, Flavonoids, Omega-3 fatty acids.},
        month = {December},
        }