Recent Advancement in Transdermal Drug Delivery System

  • Unique Paper ID: 170709
  • PageNo: 1420-1432
  • Abstract:
  • The transdermal route offers several advantages over traditional drug delivery methods. These include high bioavailability, avoidance of first-pass liver metabolism, consistent drug levels in the bloodstream, and a non-invasive approach to treatment. Furthermore, transdermal drug delivery systems (TDDS) offer prolonged therapeutic effects, fewer side effects, enhanced bioavailability, improved patient adherence, and easy discontinuation of therapy. TDDS is used not only in pharmaceuticals but also in skincare and cosmetics. Research has shown that the transdermal route causes minimal skin irritation and performs better in various in vivo tests compared to oral administration. This review article provides an in-depth analysis of TDDS, emphasizing its benefits over conventional dosage forms, discussing limitations, examining transdermal patch components, exploring various patch types, outlining preparation methods, and identifying ideal TDDS requirements. Additionally, it addresses regulatory factors, physicochemical evaluation methods, therapeutic applications, and recent progress in transdermal drug delivery systems.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{170709,
        author = {Tejashree Kuwlekar and Dr. Nitin C. Mohire and Akash S. Nalawade and Jyoti Sonawane},
        title = {Recent Advancement in Transdermal Drug Delivery System},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {1420-1432},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170709},
        abstract = {The transdermal route offers several advantages over traditional drug delivery methods. These include high bioavailability, avoidance of first-pass liver metabolism, consistent drug levels in the bloodstream, and a non-invasive approach to treatment. Furthermore, transdermal drug delivery systems (TDDS) offer prolonged therapeutic effects, fewer side effects, enhanced bioavailability, improved patient adherence, and easy discontinuation of therapy. TDDS is used not only in pharmaceuticals but also in skincare and cosmetics. Research has shown that the transdermal route causes minimal skin irritation and performs better in various in vivo tests compared to oral administration. This review article provides an in-depth analysis of TDDS, emphasizing its benefits over conventional dosage forms, discussing limitations, examining transdermal patch components, exploring various patch types, outlining preparation methods, and identifying ideal TDDS requirements. Additionally, it addresses regulatory factors, physicochemical evaluation methods, therapeutic applications, and recent progress in transdermal drug delivery systems.},
        keywords = {Tdds; Transdermal Patch; Permeation Enhancer; Partition Coefficients; Iontophoresis.},
        month = {December},
        }

Cite This Article

Kuwlekar, T., & Mohire, D. N. C., & Nalawade, A. S., & Sonawane, J. (2024). Recent Advancement in Transdermal Drug Delivery System. International Journal of Innovative Research in Technology (IJIRT), 11(7), 1420–1432.

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