A REVIEW ON NITROGEN MUSTARDS: “KEY PLAYERS IN THE FIGHT AGAINST CANCER”

  • Unique Paper ID: 171043
  • PageNo: 2796-2800
  • Abstract:
  • Among alkylating agents, nitrogen mustards are the most commonly utilized .Only five of the thousands of nitrogen mustards that has been created and tested are currently often utilized in cancer treatment -Melphalan, Cyclophosphamide, Ifosfamide, Chlorambucil and Mechlorethamine-the classic ‘nitogen mustards’-are among them. Every nitrogen mustard undergoes a reaction via an aziridinium intermediate, and the bis-chloroethyl group is the distinctive chemical component of nitrogen mustards. The rest of the molecule has an impact on the transport, distribution, and reactivity of the particular agents and is crucial in establishing the molecule’s physical characteristics.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{171043,
        author = {Ms Kollepara Phanisri Bangaru Satvika and Ms Kota Naga Komali and Ms Gudupu Devi Priya and Mrs Sharmila Manukonda and Dr V Bhaskara raju},
        title = {A REVIEW ON NITROGEN MUSTARDS: “KEY PLAYERS IN THE FIGHT AGAINST CANCER”},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {2796-2800},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=171043},
        abstract = {Among alkylating agents, nitrogen mustards are the most commonly utilized .Only five of the thousands of nitrogen mustards that has been created and tested are currently often utilized in cancer treatment -Melphalan, Cyclophosphamide, Ifosfamide, Chlorambucil and Mechlorethamine-the classic ‘nitogen mustards’-are among them. Every nitrogen mustard undergoes a reaction via an aziridinium intermediate, and the bis-chloroethyl group is the distinctive chemical component of nitrogen mustards. The rest of the molecule has an impact on the transport, distribution, and reactivity of the particular agents and is crucial in establishing the molecule’s physical characteristics.},
        keywords = {Nitrogen mustard, cancer, alkylation, DNA damage},
        month = {December},
        }

Cite This Article

Satvika, M. K. P. B., & Komali, M. K. N., & Priya, M. G. D., & Manukonda, M. S., & raju, D. V. B. (2024). A REVIEW ON NITROGEN MUSTARDS: “KEY PLAYERS IN THE FIGHT AGAINST CANCER”. International Journal of Innovative Research in Technology (IJIRT), 11(7), 2796–2800.

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