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@article{171425, author = {Mr. Suhail Anjum Rather and Mr. Pankaj Kumar and Dr. Promila Sama and Mr. Amandeep Paul and Mr. Fakir Chand and Mr. Shahid Akbar Lone}, title = {TO STUDY THE LEVEL OF CARDIAC BIOMARKERS IN PATIENTS UNDER-GOING ACUTE MYOCARDIAL INFARACTION}, journal = {International Journal of Innovative Research in Technology}, year = {2024}, volume = {11}, number = {7}, pages = {3179-3183}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=171425}, abstract = {Myocardial infarction is a condition which is mainly happens due to blockage in the flow of blood circulation e.g: in veins, arteries, blood vessels. Cardiac Biomarkers are substances that get released into the blood when the heart is damaged. Cardiac biomarkers can be detected in blood by a specialized immunoassay. They are used to help diagnosis, evaluate, and monitor patients with suspected acute coronary syndrome (ACS). Cardiac biomarkers are not necessary for the diagnosis of patients who present with ischemic chest pain and diagnostic ECG with ST segment elevation. But cardiac biomarkers are very useful in patients of non-diagnostic ECG. Material and Method: The two groups were generated from a total of 50 subjects in my research projects. 27 abnormal, 23 control-normal/ borderlines. The Mindray 200 Fully Auto Biochemistry Analyzer tested the patients' biochemistry by measuring the levels of cardiac biomarkers in the acute myocardial infarction tested like CK (Creatine kinase), CK-MB (Creatine kinase-MB), LDH (Lactate Dehydrogenase) by enzymatic reaction and Trop-I by card method. Result: The results were expressed as Mean ± SD. The statistical analysis of the data was carried out with statistical package of social sciences (SPSS), version 20.0. The comparison between two groups was tested by ‘t’ test. In most of the cases males are more affected. The values of CK in males groups of patients seen in increased levels, on the other hand the value of CK-MB in females groups of patients remined normal on or borderline, where as some of the patients from both groups shows positive results in trop-I card method test. Conclusion: it is found that appropriate study of cardiac markers like Total CK, CK-MB, LDH, , cTn-T, cTn-I is significant for the study and evaluation of myocardial infarction. Males are at higher risk than female for cardiac disease and also from my study it is found that cTn –Tis the reliable markers . Troponin-T is the best cardiac marker for detection of Myocardial Infarction (MI).}, keywords = {}, month = {December}, }
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