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@article{172107,
        author = {Kirti Rajendra Neve and Anuja Pramod Patil and Pranjal Kishor Patil and Tanvi Manohar Otari and Leena Vinayak Wagh and Gaytri Dhanraj Pingale},
        title = {NANO EMULSION FOR PARKINSON'S DISEASE},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {8},
        pages = {2248-2261},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172107},
        abstract = {Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the brain, which results in the development of symptoms such as tremors, rigidity, and bradykinesia. Traditional treatments involve symptom relief, typically through either an increase in dopamine levels or its mimetic action, but issues such as low bioavailability, dose variability, and failure to cross the BBB limit the efficacy of conventional treatments. The unique properties of nanoemulsions-which include an increase in the solubility, bioavailability, and stability of hydrophobic drugs with droplet sizes below 100 nm-make them very promising candidates for drug delivery in PD by possibly bypassing the BBB. Preparation techniques such as high-pressure homogenization, ultrasonication, and phase inversion methods in nanoemulsion-based delivery systems for PD will be reviewed here. It also points out the benefits of nanoemulsions, such as targeted delivery, sustained release, and better stability. Applications in PD management are discussed, which include drugs such as levodopa, ropinirole, and resveratrol encapsulated in nanoemulsions to improve therapeutic outcomes. Future prospects emphasize the possibility of nanoemulsions in revolutionizing neurological disease treatments by overcoming conventional drug delivery limitations and improving patient outcomes.},
        keywords = {Dopaminergic neurons, High-pressure homogenization, Neurodegenerative disorder, Neurological disease treatments, Phase inversion methods,},
        month = {January},
        }