Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{172405,
        author = {Rizwana Ashiq and Dr Abhishek Gupta and Dr Shipra and Dr Pankaj Kaul},
        title = {A Comparative Study on Lidocaine and Fentanyl in Attenuation of Hemodynamic Responses to Laryngoscopy and Intubation under General Anesthesia for Elective Surgeries},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {8},
        pages = {3090-3097},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172405},
        abstract = {Background: Laryngoscopy and intubation during general anesthesia often trigger tachycardia and hypertension due to sympathetic activation, posing risks for patients with cardiovascular conditions. Lidocaine and fentanyl are commonly used to attenuate these responses, but their comparative efficacy remains debated. Methods: The present study was conducted in the department of anesthesiology, Safdarjung Hospital New Delhi, on 50 adult patients up to the age of 35- 60 years and weight 55 – 80 kg, with ASA grading of I and II, of either gender were scheduled for elective surgeries. They were divided into two groups- group I (n=25) received inj. fentanyl 2mcg/kg iv and group II (n=25) received inj. Lidocaine 1.5mg/kg iv. Results: Both lidocaine and fentanyl significantly reduced the hemodynamic response to laryngoscopy and intubation. However, fentanyl showed a more consistent reduction in heart rate and blood pressure compared to lidocaine, especially during the immediate post-intubation period. There were no significant differences in adverse effects between the two groups.Conclusion: Fentanyl is more effective than lidocaine in attenuating hemodynamic responses during laryngoscopy and intubation under general anesthesia.},
        keywords = {Laryngoscopy, Intubation, Hemodynamic response, Fentanyl, Lidocaine},
        month = {January},
        }