Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{172485,
        author = {Arpita Srivastava and Megha Agrawal and Sharda Darro and Labya Prabhas and Arunima Sur},
        title = {Phytochemical Insights and Antibacterial Efficacy of Andrographis paniculata from Chhattisgarh Against UTI Pathogens},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {9},
        pages = {60-66},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172485},
        abstract = {Urinary tract infections (UTIs) are among the most common infections worldwide, increasingly complicated by rising antimicrobial resistance. Approximately 40% of women and 12% of men experience symptomatic UTIs at least once in their lifetime. However, the growing resistance of UTI-causing bacteria to conventional antibiotics presents a significant challenge in managing this condition. The implications of antibiotic resistance include increased mortality and morbidity, posing serious risks to patients, particularly in cases of severe or chronic infections. This study investigates the phytochemical composition and antimicrobial activity of Andrographis paniculata against UTI-causing pathogens. Leaf extracts of Andrographis paniculata, obtained using chloroform, methanol, and distilled water as solvents, were evaluated for antibacterial efficacy against both Gram-positive and Gram-negative pathogens. The results revealed that the plant exhibited notable antibacterial activity, indicating its potential as a natural antimicrobial agent. These findings suggest that Andrographis paniculata holds promise for the development of natural compounds that could lead to the creation of innovative pharmaceuticals. Such advancements would address the critical therapeutic needs posed by antibiotic-resistant UTIs, offering a valuable and sustainable solution for treating this widespread health issue in the future.},
        keywords = {Antimicrobial activity, pathogens, Andrographis paniculata, chloroform, methanol, Urinary tract infection.},
        month = {January},
        }