The role of chitosan in Regenerative Endodontics : A Review of Current Advances and Future Directions

  • Unique Paper ID: 173745
  • PageNo: 1426-1429
  • Abstract:
  • Chitosan, a biopolymer derived from chitin, has gained attention in regenerative endodontics due to its biocompatibility, antibacterial properties, and capacity to promote tissue regeneration. This review explores the applications of chitosan in endodontics, particularly its role in scaffold development for pulp regeneration and as a drug delivery system for antibiotics and growth factors. Chitosan-based scaffolds exhibit excellent cellular compatibility, encouraging the proliferation and differentiation of dental pulp stem cells. The incorporation of chitosan into antibiotic formulations, enhances antimicrobial efficacy while mitigating cytotoxic effects of the drug .Innovations in chitosan, including nanoparticles and hydrogels, are showing promising clinical outcomes. This review aims to consolidate current findings and discuss the challenges and future prospects of chitosan in regenerative endodontics, emphasizing its potential to revolutionize treatment protocols and enhance treatment outcomes.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{173745,
        author = {Dr.Asiya Mujawar and Dr.Varsha Pandit},
        title = {The role of chitosan in Regenerative Endodontics : A Review of Current Advances and Future Directions},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {1426-1429},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=173745},
        abstract = {Chitosan, a biopolymer derived from chitin, has gained attention in regenerative endodontics due to its biocompatibility, antibacterial properties, and capacity to promote tissue regeneration. This review explores the applications of chitosan in endodontics, particularly its role in scaffold development for pulp regeneration and as a drug delivery system for antibiotics and growth factors. Chitosan-based scaffolds exhibit excellent cellular compatibility, encouraging the proliferation and differentiation of dental pulp stem cells. The incorporation of chitosan into antibiotic formulations, enhances antimicrobial efficacy while mitigating cytotoxic effects of the drug .Innovations in chitosan, including nanoparticles and hydrogels, are showing promising clinical outcomes. This review aims to consolidate current findings and discuss the challenges and future prospects of chitosan in regenerative endodontics, emphasizing its potential to revolutionize treatment protocols and enhance treatment outcomes.},
        keywords = {Chitosan, Endodontics, Biomaterials, Antimicrobial Activity, Regenerative Dentistry, Drug Delivery , Outcome},
        month = {March},
        }

Cite This Article

Mujawar, D., & Pandit, D. (2025). The role of chitosan in Regenerative Endodontics : A Review of Current Advances and Future Directions. International Journal of Innovative Research in Technology (IJIRT), 11(10), 1426–1429.

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