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@article{174315,
        author = {Dr. SHAH KAVINA KALPESH and Dr. Mahantesh V. Patil and Dr. Roshni R},
        title = {LUPUS NEPHRITIS IN CHILDHOD: A CASE REPORT HIGHLIGHTING THE CHALLENGES OF DISEASE MANAGEMENT},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {3382-3384},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=174315},
        abstract = {Background: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), affecting renal function through immune complex deposition. While it is more common in adults, pediatric lupus nephritis presents aggressive courses, often requiring immunosuppression and dialysis.
Case Presentation: A 14-year-old female with a history of SLE presented with progressive renal failure, uncontrolled hypertension, and generalized edema. Laboratory tests confirmed lupus nephritis (Class IV), leading to end-stage kidney disease (ESKD). Despite aggressive immunosuppressive therapy, she required urgent hemodialysis initiation due to worsening renal function. The management included antihypertensive therapy, steroids, and mycophenolate mofetil, but her dependency on dialysis persisted.
Conclusion: Pediatric lupus nephritis poses significant diagnostic and therapeutic challenges. Early recognition, aggressive treatment, and optimal blood pressure control are crucial to improve outcomes. This case highlights the need for individualized management and long-term follow-up in pediatric LN patients.},
        keywords = {},
        month = {March},
        }