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@article{174732,
        author = {Pranjal Vijay Dutte and Vaishnavi Gajanan Wagh and Siddhi Milind Badgujar and Kapil Nana Patil},
        title = {A Review On In-situ Gel},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {11},
        pages = {534-544},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=174732},
        abstract = {The present review on in situ gelling systems has emerged as a significant and widely recognized topic within the field. These systems offer substantial advantages for drug delivery, characterized by their ease of use and straightforward manufacturing processes. They enhance patient adherence and comfort by reducing the frequency of drug administration, attributed to their distinctive sol-to-gel transition properties. The formation of gels is influenced by various factors, including temperature variations, pH alterations, ionic presence, and exposure to UV light. The gels formed in situ facilitate the sustained and controlled release of drugs. Both natural and synthetic biodegradable polymers, such as pectin, alginic acid, gellan gum, and xyloglucan, are utilized in the formulation of these gels. This review focused definitions, classifications, benefits, drawbacks, and the types of polymers employed, along with their desirable characteristics and preparation methods for in situ gels. Additionally, it addresses the approaches, applications, and evaluation methods pertinent to in situ gels.},
        keywords = {In situ gel, Mechanism, Novel drug delivery system, Polymers.},
        month = {March},
        }