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@article{174775, author = {NEHA JAGDISH AGARKAR and JEEVESH RAMJI MALVIYA and Krutika channe}, title = {Molecular Pathways Linking Chronic Stress, Diet, and Cardiovascular Health}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {11}, pages = {601-608}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=174775}, abstract = {Chronic stress and diet are significant yet often interlinked factors influencing cardiovascular diseases (CVDs). This review explores the key molecular pathways connecting chronic stress to cardiovascular dysfunction, including dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, sympathetic nervous system (SNS) overactivation, oxidative stress, and systemic inflammation. Additionally, we examine the role of diet in either exacerbating or mitigating stress-induced cardiovascular effects. Special attention is given to the gut microbiota as a mediator, epigenetic modifications influencing CVD risk, and potential therapeutic strategies such as dietary interventions and stress management techniques. Understanding these complex interactions could lead to novel preventative and therapeutic approaches for cardiovascular health [1, 2, 3].}, keywords = {Chronic Stress, Cardiovascular Diseases, HPA Axis, Sympathetic Nervous System, Inflammation, Oxidative Stress, Gut Microbiota, Epigenetics, Stress-Induced Eating, Metabolic Syndrome, Heart Disease Prevention.}, month = {March}, }
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