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@article{175567, author = {Dr. Sanchita Sinha}, title = {Metal-thiosemicarbazone Complexes - Biological Activity & Structural Studies}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {11}, pages = {3460-3464}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=175567}, abstract = {Thiosemicarbazones is an important compounds of N S-donor atoms, that have been several biological properties. Thiosemicarbazones (TSCs) posses antibacterial, anti-viral, anti-tumar and anti-fungal properties. Activity of the N-S ligands influences by the presence of a metal ion.TSCs compounds uses in the extraction and determination of metal ions. Recently synthesis of anti-tumar complexes like cis-platin Pt (II) and Pd (II) chelates with N S-ligands etc., more attention towards the synthesis of these complexes. TSCs complex posses structure dissimilarity, different bonding patterns, potent biological application and ion sensing properties. Present investigation gives detailed description of synthesis, structural studies and biological applications of metal- Thiosemicarbazones chelates. The relations between structural and biological properties of metal N-S ligand complexes of different stoichiometries has been also reviewed.}, keywords = {Metal complex, Thiosemicarbazones, Chelating ligand, anti-microbial activity, anti-tumor properties, anti-viral properties, Heteroleptic ligand etc.}, month = {April}, }
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