Effect of Lemon Juice on Serum Cholesterol of Albino Mice (Mus musculus)

  • Unique Paper ID: 175977
  • PageNo: 4472-4476
  • Abstract:
  • This study investigates the effect of lemon juice on serum cholesterol levels in albino mice (Mus musculus). Hypercholesterolemia is a significant risk factor for cardiovascular diseases, and natural dietary interventions, such as citrus juices, have been proposed to modulate cholesterol levels. The experiment used two groups of albino mice: a control group receiving distilled water and a hyperlipidaemic test group receiving a high-fat diet (10 mL/kg body weight) and lemon juice extract (20 mL/kg/day) for 35 days. Serum cholesterol levels were measured before and after the intervention. Statistical analysis was performed using SPSS to determine the significance of changes. The results indicate a significant reduction in serum cholesterol levels in the treated group, suggesting the potential cholesterol-lowering effect of lemon juice.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{175977,
        author = {David and Dr. Dinesh Yadav},
        title = {Effect of Lemon Juice on Serum Cholesterol of Albino Mice (Mus musculus)},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {11},
        pages = {4472-4476},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=175977},
        abstract = {This study investigates the effect of lemon juice on serum cholesterol levels in albino mice (Mus musculus). Hypercholesterolemia is a significant risk factor for cardiovascular diseases, and natural dietary interventions, such as citrus juices, have been proposed to modulate cholesterol levels. The experiment used two groups of albino mice: a control group receiving distilled water and a hyperlipidaemic test group receiving a high-fat diet (10 mL/kg body weight) and lemon juice extract (20 mL/kg/day) for 35 days. Serum cholesterol levels were measured before and after the intervention. Statistical analysis was performed using SPSS to determine the significance of changes. The results indicate a significant reduction in serum cholesterol levels in the treated group, suggesting the potential cholesterol-lowering effect of lemon juice.},
        keywords = {},
        month = {April},
        }

Cite This Article

David, , & Yadav, D. D. (2025). Effect of Lemon Juice on Serum Cholesterol of Albino Mice (Mus musculus). International Journal of Innovative Research in Technology (IJIRT), 11(11), 4472–4476.

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