Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{177174,
        author = {Sathvik Madagi and Riithun S and Dr. Narendra Kumar S},
        title = {A Review on Targeted Drug Delivery using Nanoparticles: A 2D Simulation Approach},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {110-114},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=177174},
        abstract = {Targeted drug delivery using nano-particles is an innovative and rapidly evolving approach that aims to enhance the therapeutic efficacy of drugs while minimizing effects in healthy parts of the body. Nano-particles have unique physio chemical properties(small size, high surface area to volume ratio), which enables precise delivery of drugs to the target site. A wide range of nano-carriers, such as liposomes, metal based nanostructures are developed which can not only encap sulate but also carry drugs. They can also be engineered with targeting ligands or small molecules that recognize specific markers ex- pressed on diseased cells, thereby facilitating active targeting. In cases of cancer treatment, nano-particles can be used as stimuli responsive , which are capable to release drugs based upon internal conditions such as pH, enzymesnredox condtions etc. Despite preclinical research, several challenges reamin in translating the nano-particle based systems into clinical practices due to issues sucha s stability, bio-compatibiltity, large scale manufacturing and majorly approvals from the governments.},
        keywords = {Targeted Drug Delivery, Nanoparticles, Simulation, Drug Release, 2D Modeling.},
        month = {April},
        }