Formulation and evaluation of Anti-Diabetics injectable on Gymnema sylvestre

  • Unique Paper ID: 179314
  • PageNo: 9232-9235
  • Abstract:
  • Gymnema Sylvestre R. Br. (Asclepiadaceae) is a herb distributed throughout the world. The leaves of the plant are widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines. Gymnemic acid is the main active chemical constituent isolated from the Gymnema Sylvestre plant. The plant is documented to possess beneficial effects as digestive, anti-inflammatory, diuretic, hypoglycemic and antihelmentic. It is believed to be used in dyspepsia, constipation, jaundice, haemorrhoids, cardiopathy, asthma, bronchitis and leucoderma.Gymnema sylvestre formulation having in the form of Tablets, Capsules, Tinctures, Powders and Teas. The Triterpenoids Saponins, Gymnemic Acids, are responsible for therapeutic benefit of the plant. However Poor solubility and low bioavailability affect efficacy of the G. Sylvestre. So, the formulation development may be a better option for improvement in pharmacodynamics and pharmacokinetics profile of the medicinal plant leading to enhanced bioavailability, therapeutic efficiency with dose reduction. the research contributes to formulation aspects of G. Sylvestre

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{179314,
        author = {Nikita Kailas Rahane and Sakshi sudhakar Nehe and Proff. Manjusha B.Aher},
        title = {Formulation and evaluation of Anti-Diabetics injectable on Gymnema sylvestre},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {9232-9235},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=179314},
        abstract = {Gymnema Sylvestre R. Br. (Asclepiadaceae) is a herb distributed throughout the world. The leaves of the plant are widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines. Gymnemic acid is the main active chemical constituent isolated from the Gymnema Sylvestre plant. The plant is documented to possess beneficial effects as digestive, anti-inflammatory, diuretic, hypoglycemic and antihelmentic. It is believed to be used in dyspepsia, constipation, jaundice, haemorrhoids, cardiopathy, asthma, bronchitis and leucoderma.Gymnema sylvestre formulation having in the form of Tablets, Capsules, Tinctures, Powders and Teas. The Triterpenoids Saponins, Gymnemic Acids, are responsible for therapeutic benefit of the plant. However Poor solubility and low bioavailability affect efficacy of the G. Sylvestre. So, the formulation development may be a better option for improvement in pharmacodynamics and pharmacokinetics profile of the medicinal plant leading to enhanced bioavailability, therapeutic efficiency with dose reduction. the research contributes to formulation aspects of G. Sylvestre},
        keywords = {},
        month = {June},
        }

Cite This Article

Rahane, N. K., & Nehe, S. S., & B.Aher, P. M. (2025). Formulation and evaluation of Anti-Diabetics injectable on Gymnema sylvestre. International Journal of Innovative Research in Technology (IJIRT), 11(12), 9232–9235.

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