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@article{179315,
        author = {Dr.Kotresh Yaligar and Dr.Madhulatha Boyapati and Mr.Pranav Phate and Ms. Samiksha Upadhye and Mr. Deepanshu Powar and Ms.Prajkta Shendage},
        title = {Investigating the Anti-Anxiety Properties of Ammannia baccifera L in Zebrafish Behavioural Models},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {8120-8125},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=179315},
        abstract = {Neurodegenerative disorders, characterized by 
the progressive loss of neuronal structure and function, 
remain a major global health challenge with limited 
therapeutic 
options. Ammannia 
baccifera L., 
a 
traditionally used medicinal plant known for its diverse 
pharmacological properties, has not been extensively 
evaluated for its potential neurotoxicity. This study aims 
to assess the neurodegenerative effects of Ammannia 
baccifera L. using zebrafish (Daniorerio) as a model 
organism, due to its well-established genetic, anatomical, 
and behavioural parallels with human neurobiology. 
Ethanolic extracts of A. baccifera were administered to 
adult zebrafish at varying concentrations over a defined 
exposure period. Behavioral assessments including 
locomotor activity, anxiety-like responses (using the 
novel tank diving test), were conducted to evaluate 
neurological function.  
Anxiolytic activity of the ethanolic whole plant extract of 
Ammania bacciferaL was performed using Novel Tank 
Diving Test &Locomotory Activity. All the treated groups 
showed significant level at P<0.05 and P<0.001 
compared with control. These results provide important 
insights into the safety profile of Ammannia baccifera, 
emphasizing the need for cautious evaluation of its 
traditional use and guiding further pharmacological 
research. This research also shows both herbal and 
drug-based treatment options, acknowledging the 
limitations and side effects of current medications and 
the potential of natural products in managing 
neurological illness symptoms.},
        keywords = {Neurodegeneration, Ammannia baccifera L,  Herbal Medicine, Anxiolytic Activity, Zebrafish Model,  etc},
        month = {May},
        }