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@article{180730,
author = {Alok Kumar Upadhyay and Prabhudutta Panda},
title = {A Comprehensive review of a novel tool for drug delivery: Ethosomes},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {1},
pages = {3421-3431},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=180730},
abstract = {Ethosomes
enable
the
non-invasive
transportation of drugs to the upper layer that is
subcutaneous layers of the skin and into the
bloodstream. Despite the complicated conceptual
foundations of these ethosomal systems, they are simple
to create and secure to utilise, significantly expanding
their
potential applications. To regulate drug
distribution and subsequent skin tissue absorption, a
number of transdermal therapy methods are there for
topical administration to the skin layer. The vesicular
approach, which has been used to overcome the obstacle
of transdermal drug administration, will be discussed in
this review. A number of studies on ethosomes in
medicine are also covered.
The ethosomes are formulated using a variety of
techniques that is recently developed for synthesizing
ethosomes that is mentioned in the review. Upon
composition, ethosomes can be subjected to a range of
characterization tests, including as stability, in vitro
permeability, pH, particle size, and zeta potential. This
part
summarizes the most current ethosome
modifications based on various pharmacological dose
forms, including as patches, gels, and creams. A brief
review of updated ethosome patents is also provided. To
summarize, ethosome is an excellent delivery
mechanism for drugs and cosmetics. The increased
transportation of chemical agents through epidermal
and cellular membranes via an ethosomal carrier poses
a number of further research and development of
enhanced medicines present difficulties and
opportunities.},
keywords = {Ethosomes, Vesicular Carriers, skin permeation, transdermal drug delivery},
month = {June},
}
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