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@article{180730, author = {Alok Kumar Upadhyay and Prabhudutta Panda}, title = {A Comprehensive review of a novel tool for drug delivery: Ethosomes}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {1}, pages = {3421-3431}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=180730}, abstract = {Ethosomes enable the non-invasive transportation of drugs to the upper layer that is subcutaneous layers of the skin and into the bloodstream. Despite the complicated conceptual foundations of these ethosomal systems, they are simple to create and secure to utilise, significantly expanding their potential applications. To regulate drug distribution and subsequent skin tissue absorption, a number of transdermal therapy methods are there for topical administration to the skin layer. The vesicular approach, which has been used to overcome the obstacle of transdermal drug administration, will be discussed in this review. A number of studies on ethosomes in medicine are also covered. The ethosomes are formulated using a variety of techniques that is recently developed for synthesizing ethosomes that is mentioned in the review. Upon composition, ethosomes can be subjected to a range of characterization tests, including as stability, in vitro permeability, pH, particle size, and zeta potential. This part summarizes the most current ethosome modifications based on various pharmacological dose forms, including as patches, gels, and creams. A brief review of updated ethosome patents is also provided. To summarize, ethosome is an excellent delivery mechanism for drugs and cosmetics. The increased transportation of chemical agents through epidermal and cellular membranes via an ethosomal carrier poses a number of further research and development of enhanced medicines present difficulties and opportunities.}, keywords = {Ethosomes, Vesicular Carriers, skin permeation, transdermal drug delivery}, month = {June}, }
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