A Comprehensive review of a novel tool for drug delivery: Ethosomes

  • Unique Paper ID: 180730
  • Volume: 12
  • Issue: 1
  • PageNo: 3421-3431
  • Abstract:
  • Ethosomes enable the non-invasive transportation of drugs to the upper layer that is subcutaneous layers of the skin and into the bloodstream. Despite the complicated conceptual foundations of these ethosomal systems, they are simple to create and secure to utilise, significantly expanding their potential applications. To regulate drug distribution and subsequent skin tissue absorption, a number of transdermal therapy methods are there for topical administration to the skin layer. The vesicular approach, which has been used to overcome the obstacle of transdermal drug administration, will be discussed in this review. A number of studies on ethosomes in medicine are also covered. The ethosomes are formulated using a variety of techniques that is recently developed for synthesizing ethosomes that is mentioned in the review. Upon composition, ethosomes can be subjected to a range of characterization tests, including as stability, in vitro permeability, pH, particle size, and zeta potential. This part summarizes the most current ethosome modifications based on various pharmacological dose forms, including as patches, gels, and creams. A brief review of updated ethosome patents is also provided. To summarize, ethosome is an excellent delivery mechanism for drugs and cosmetics. The increased transportation of chemical agents through epidermal and cellular membranes via an ethosomal carrier poses a number of further research and development of enhanced medicines present difficulties and opportunities.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{180730,
        author = {Alok Kumar Upadhyay and Prabhudutta Panda},
        title = {A Comprehensive review of a novel tool for drug delivery: Ethosomes},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {1},
        pages = {3421-3431},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=180730},
        abstract = {Ethosomes 
enable 
the 
non-invasive 
transportation of drugs to the upper layer that is 
subcutaneous layers of the skin and into the 
bloodstream. Despite the complicated conceptual 
foundations of these ethosomal systems, they are simple 
to create and secure to utilise, significantly expanding 
their 
potential applications. To regulate drug 
distribution and subsequent skin tissue absorption, a 
number of transdermal therapy methods are there for 
topical administration to the skin layer. The vesicular 
approach, which has been used to overcome the obstacle 
of transdermal drug administration, will be discussed in 
this review. A number of studies on ethosomes in 
medicine are also covered. 
The ethosomes are formulated using a variety of 
techniques that is recently developed for synthesizing 
ethosomes that is mentioned in the review. Upon 
composition, ethosomes can be subjected to a range of 
characterization tests, including as stability, in vitro 
permeability, pH, particle size, and zeta potential. This 
part 
summarizes the most current ethosome 
modifications based on various pharmacological dose 
forms, including as patches, gels, and creams. A brief 
review of updated ethosome patents is also provided. To 
summarize, ethosome is an excellent delivery 
mechanism for drugs and cosmetics. The increased 
transportation of chemical agents through epidermal 
and cellular membranes via an ethosomal carrier poses 
a number of further research and development of 
enhanced medicines present difficulties and 
opportunities.},
        keywords = {Ethosomes, Vesicular Carriers, skin  permeation, transdermal drug delivery},
        month = {June},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 12
  • Issue: 1
  • PageNo: 3421-3431

A Comprehensive review of a novel tool for drug delivery: Ethosomes

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