Targeting Inflammation: Recent Advances in Antiarthritic Therapies from Natural and Synthetic Origins

  • Unique Paper ID: 181881
  • PageNo: 366-381
  • Abstract:
  • Arthritis, particularly rheumatoid arthritis and osteoarthritis, remains a major global health challenge owing to its chronic, inflammatory, and degenerative nature. Current treatments aim to reduce inflammation and prevent joint damage, but often have limitations, such as side effects and cost. This review explores recent developments in antiarthritic therapies, focusing on both natural (plant-based compounds and nutraceuticals) and synthetic (NSAIDs, DMARDs, and biologics) approaches. Emphasis is placed on the molecular targets, mechanisms of action, and comparative efficacy. The integration of traditional remedies and modern pharmacology presents new hope for safe, effective, and affordable management of arthritis.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{181881,
        author = {Kale Abhijeet B. and Bindu A. U. and Suryawanshi Sandeep B.},
        title = {Targeting Inflammation: Recent Advances in Antiarthritic Therapies from Natural and Synthetic Origins},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {366-381},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=181881},
        abstract = {Arthritis, particularly rheumatoid arthritis and osteoarthritis, remains a major global health challenge owing to its chronic, inflammatory, and degenerative nature. Current treatments aim to reduce inflammation and prevent joint damage, but often have limitations, such as side effects and cost. This review explores recent developments in antiarthritic therapies, focusing on both natural (plant-based compounds and nutraceuticals) and synthetic (NSAIDs, DMARDs, and biologics) approaches. Emphasis is placed on the molecular targets, mechanisms of action, and comparative efficacy. The integration of traditional remedies and modern pharmacology presents new hope for safe, effective, and affordable management of arthritis.},
        keywords = {Anti-arthritic, inflammatory, natural compounds, synthetic drugs, rheumatoid arthritis, phytochemicals, NSAIDs, DMARDs, cytokines.},
        month = {July},
        }

Cite This Article

B., K. A., & U., B. A., & B., S. S. (2025). Targeting Inflammation: Recent Advances in Antiarthritic Therapies from Natural and Synthetic Origins. International Journal of Innovative Research in Technology (IJIRT), 12(2), 366–381.

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