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@article{181980,
author = {Sandhya suresh and Dev soni and pankaj mali and mahendra kumar and vishal joshi and aavesh mehta and Dr. Raghvendra Singh Bhadauria},
title = {A REVIEW ON PHARMACOLOGICAL ACTIVITIES OF CARICA PAPAYA},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {2},
pages = {233-241},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=181980},
abstract = {Carica papaya Linn., commonly known as papaya, is a well-known tropical plant extensively cultivated for its nutritional and medicinal properties. This review highlights the wide range of pharmacological activities associated with various parts of C. papaya, including its leaves, fruit, seeds, and roots. Phytochemical investigations reveal that C. papaya is rich in bioactive compounds such as alkaloids, flavonoids, tannins, saponins, and the proteolytic enzyme papain. These constituents contribute to its significant antioxidant, anti-inflammatory, antimicrobial, hepatoprotective, antidiabetic, anticancer, and immunomodulatory activities. Notably, the leaf extract has shown promise in managing dengue fever by improving platelet counts. The seeds exhibit potent anthelmintic and contraceptive effects, offering natural alternatives for parasite control and fertility regulation. Additionally, extracts from C. papaya have demonstrated wound healing, gastroprotective, and hepatoprotective effects in various experimental models. While preclinical studies have established a strong pharmacological basis, further clinical trials and standardization are necessary to ensure efficacy and safety for wider therapeutic use. This review aims to consolidate current findings, promote the understanding of the plant’s therapeutic potential, and encourage future research to isolate, characterize, and develop novel formulations derived from Carica papaya. Expanding scientific validation and sustainable utilization could help harness this versatile plant as an affordable and accessible source of natural medicine.},
keywords = {Carica papaya, papain, pharmacological activities, antioxidant, anti-inflammatory, antidiabetic, antimicrobial, traditional medicine},
month = {June},
}
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