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@article{182238,
        author = {DR HARDH RAJGURU and DR JANAK CHOKSHI and DR AKASH PATEL and DR KRISHN UNDAVIYA and DR YESHA PATEL},
        title = {Cardiac Manifestations in PLHA and Their Correlation with HIV Viral Load},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {1565-1567},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=182238},
        abstract = {Background: The introduction of highly active antiretroviral therapy (HAART) has significantly improved the clinical evolution of HIV/AIDS, with an increased survival of infected patients. With advances in the management of patients living with HIV and AIDS, not only has survival increased but manifestations of late-stage PLHA are encountered more often, including cardiovascular complications.
Objectives:
 To determine the prevalence and characteristics of cardiac manifestations in patients with PLHA, and to correlate the cardiac manifestations with HIV viral loadMethods: 115 PLHA cases and 30 healthy control subjects were evaluated. HIV viral load was measured using quantitative PCR. Cardiac evaluation included detailed history, general physical examination, and echocardiographic assessment.
Results:
 Echocardiographic abnormalities were found in 63% of the cases compared with 6% in the controls. Higher viral loads were associated with increased incidence of pericardial effusion, diastolic dysfunction, dilated cardiomyopathy, pulmonary artery hypertension, mitral valve prolapse, and reduced ejection fraction. Most abnormalities were concentrated in pastients with high HIV viral load (>100,000 copies/mL). 
Conclusions:
 Cardiovascular abnormalities in PLHA patients are common and can occur without any clinical manifestation. There was a significant association between high HIV viral load and cardiac abnormalities.},
        keywords = {},
        month = {July},
        }