The Cellular Signalling Landscape of Migraine: Insights into Pathophysiology and Intervention

  • Unique Paper ID: 182354
  • PageNo: 2022-2024
  • Abstract:
  • Migraine is a complex neurological disorder characterised by recurrent headaches1 and associated symptoms such as photophobia, phonophobia, and nausea. Recent advances in neurobiology have highlighted the pivotal role of cell signalling pathways in the pathogenesis of migraine2. This review synthesises current knowledge on the involvement of neuronal, glial, and immune cell signalling in migraine, focusing on molecular mediators, genetic factors, and neuroinflammatory processes. We discuss the implications of these findings for the development of targeted therapies and future research directions.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{182354,
        author = {KARTIKEY and prof Dr Dinesh chandra shastri},
        title = {The Cellular Signalling Landscape of Migraine: Insights into Pathophysiology and Intervention},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {2022-2024},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=182354},
        abstract = {Migraine is a complex neurological disorder characterised by recurrent headaches1 and associated symptoms such as photophobia, phonophobia, and nausea. Recent advances in neurobiology have highlighted the pivotal role of cell signalling pathways in the pathogenesis of migraine2. This review synthesises current knowledge on the involvement of neuronal, glial, and immune cell signalling in migraine, focusing on molecular mediators, genetic factors, and neuroinflammatory processes. We discuss the implications of these findings for the development of targeted therapies and future research directions.},
        keywords = {cell signal, migraine},
        month = {July},
        }

Cite This Article

KARTIKEY, , & shastri, P. D. D. C. (2025). The Cellular Signalling Landscape of Migraine: Insights into Pathophysiology and Intervention. International Journal of Innovative Research in Technology (IJIRT), 12(2), 2022–2024.

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