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@article{182722,
        author = {Sanskruti rajendra kathar. and Amanpreet Kaur Dumda},
        title = {Evaluation and development of polyherbal oral film : a novel approach for the treatment of toothache, dental caries and Oral Infections},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {3058-3066},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=182722},
        abstract = {Oral disease and oral infections is still a major Public health problem across the globe. Toothache, dental caries are one of human's oldest and most prevalent diseases.
The present study aimed to develop and evaluate Polyherbal oral dissolving Films commonly known as orodispersible Films [ODFs] From Four Selective combinations of herbal extracts For the management of oral health issues.
This study Focused on the incorporation into orodispersible Films [ODFs] of the herbal extracts Of Thyme Vulgaris, Annona squamosa (b), Mentha piperita and Syzygium aromaticum (Clove) Against bacteria like Streptococcus mutans.
The Films were formulated using a blend of Polymers and plasticizers and their physical chemical, mechanical and antimicrobial Properties were evaluated. The antimicrobial Properties of the poly herbal Films and Standard Marketed Formulations Such as mouthwash were evaluated against the dental Pathogens S. mutans.
The Zone of inhibition produced by Standard marketed Formulation is less than the Polyherbal Films. These results indicated that the " mouth dissolving Poly herbal Films Could be effective in the treatment of toothache, dental caries and oral infections.
The Polyherbal oral Films demonstrated Promising result's With good tensile strength, Flexible and antimicrobial activity against Oral Pathogens. The Film also showed Sustained release of herbal extract, indicating their potential For Prolonged therapeutic effects, The developed Polyherbal Oral Films Offers a Novel and effective approach for the management of oral issues provide a convenient and patient friendly dosage form.},
        keywords = {Annona squamosa (b), Antimicrobial activity, Convenient and patient friendly dosage form, Hot Melt Extrusion Mentha piperita, Novel and effective approach, Orodispersible Films [ODFs], Oral Pathogens, Syzygium aromaticum (Clove), Solvent casting, Sustained release of herbal extract, Tensile strength, Thyme Vulgaris.},
        month = {July},
        }