Recent Developments of Exosome Therapeutic Approaches in Neurodegeneration

  • Unique Paper ID: 183460
  • PageNo: 1840-1842
  • Abstract:
  • The neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease, are characterized by gradual neuronal impairment and loss. Even with improved understanding of their pathophysiology, efficacious therapeutic approaches are still scarce. Exosomes.nano.vesicles of the extracellular compartment.have emerged as therapeutic hopefuls because they can cross the blood-brain barrier (BBB), are biocompatible, and can facilitate intercellular communication. Here, we review recent advancements in the development of exosomes as therapeutic delivery vehicles for molecules, regulators of neuroinflammation, and biomarkers for the diagnosis of neurodegenerative diseases. We also discuss the hurdles of taking exosome-based therapies from the bench to the bedside and suggest directions for future research.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{183460,
        author = {Dr. Vijendra Rao and Devesh Kumar Tewary},
        title = {Recent Developments of Exosome Therapeutic Approaches in Neurodegeneration},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {3},
        pages = {1840-1842},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=183460},
        abstract = {The neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease, are characterized by gradual neuronal impairment and loss. Even with improved understanding of their pathophysiology, efficacious therapeutic approaches are still scarce. Exosomes.nano.vesicles of the extracellular compartment.have emerged as therapeutic hopefuls because they can cross the blood-brain barrier (BBB), are biocompatible, and can facilitate intercellular communication. Here, we review recent advancements in the development of exosomes as therapeutic delivery vehicles for molecules, regulators of neuroinflammation, and biomarkers for the diagnosis of neurodegenerative diseases. We also discuss the hurdles of taking exosome-based therapies from the bench to the bedside and suggest directions for future research.},
        keywords = {Exosomes, neurodegeneration, Alzheimer's disease, Parkinson's disease, blood-brain barrier, biomarkers, drug delivery},
        month = {August},
        }

Cite This Article

Rao, D. V., & Tewary, D. K. (2025). Recent Developments of Exosome Therapeutic Approaches in Neurodegeneration. International Journal of Innovative Research in Technology (IJIRT), 12(3), 1840–1842.

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