Bioactive Evaluation of the Protox Inhibitory Potential of Quercetin

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Vishal Banewar; Chaitra Shriyan

Bioactive Evaluation of the Protox Inhibitory Potential of Quercetin

Authors: Vishal Banewar, Chaitra Shriyan

Unique Paper ID: 183588
Volume: 12
Issue: 3
PageNo: 2076-2079

Keywords: Quercetin Protox LD-50 Toxicity

Abstract:
A common flavonoid found in common foods like fruits and vegetables, quercetin is well-known for its health benefits, which include lowering edema, combating oxidation, and even preventing cancer. However, we have to overlook the potential drawbacks—its toxicity, particularly when it comes to modified forms utilized in treatments. In this study, we examined the oral toxicity of quercetin and three related chemicals using computer-based predictions through ProTox-3.0. Lethal dosages (LD50), toxicity levels, organ impacts, and their interactions with bodily pathways were among the parameters we studied. With an LD50 of 159 mg/kg (class 3), quercetin may be moderately hazardous, according to our data; however, the variations appear to be safer at 5000 mg/kg (class 5). They are all at risk for lung and kidney problems, as well as certain receptor interactions. This gives us a better idea of their safety, though real-lab tests are still needed. For initial checks, computer techniques such as these are quick, humane, and animal-free.

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Cite This Article

ISSN: 2349-6002
Volume: 12
Issue: 3
PageNo: 2076-2079

Bioactive Evaluation of the Protox Inhibitory Potential of Quercetin

Available:https://ijirt.org/article?manuscript=183588

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

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