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@article{183673,
        author = {Vinit Singh and Satyam Kumar and Aditya Mishra and Aditya Kumar},
        title = {Nanotechnology in Drug Delievery system},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {3},
        pages = {2425-2432},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=183673},
        abstract = {Nanotechnology offers transformative capabilities in drug delivery systems by enabling the precise engineering of materials at the nanoscale, typically within the 1–100 nm range. This review explores recent advancements in nanocarrier technologies—including liposomes, dendrimers, polymeric nanoparticles, and quantum dots—that facilitate targeted, controlled, and sustained delivery of therapeutic agents. These nanosystems improve drug bioavailability, reduce systemic toxicity, and enable site-specific targeting, which is particularly beneficial in treating complex diseases such as cancer and neurodegenerative disorders. Surface functionalization with targeting ligands further enhances selectivity and therapeutic efficacy. Notably, nanomaterials such as chitosan, PLGA, and peptide-based nanotubes have been successfully employed for the delivery of anti-cancer drugs and RNAi therapeutics. The ability of nanoparticle systems to traverse biological barriers, such as the blood-brain barrier, underscores their potential in treating brain malignancies. Additionally, nanotechnologies targeting molecular pathways involving VEGF and cell adhesion molecules represent promising strategies for disease modulation. Despite these advances, challenges remain in terms of nanoparticle toxicity, biocompatibility, scalability, and regulatory approval. This review outlines key developments and identifies future directions where nanotechnology can address critical limitations in current drug delivery paradigms, positioning it as a vital tool in the evolution of precision medicine.},
        keywords = {Nanotechnology, Drug Delivery, Nanoscale, Liposomes, Quantum Dots, Bioavailability, PLGA, RNAi, VEGF & etc.},
        month = {August},
        }