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@article{183708,
        author = {Satish Kalshetty and Dr. Amit kumar and Dr. Mohd Rafiq},
        title = {Preparation And Evaluation Of Antidiabetic And Antihyperlipidemic Activities Of Polyherbal Formulation In Alloxan Induced Diabetic Rat},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {3},
        pages = {2841-2848},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=183708},
        abstract = {The present study focuses on the preparation and evaluation of antidiabetic and antihyperlipidemic activities of a polyherbal formulation in Alloxan-induced diabetic rats. Diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia and dyslipidemia, poses a significant global health burden. Herbal medicines, owing to their multifaceted therapeutic potential and minimal side effects, have gained prominence in the management of diabetes and associated lipid abnormalities.
A polyherbal formulation (Semecarpus anacardium, Portulaca quadrifida and Acacia nilotica) was developed using selected medicinal plants traditionally known for their antidiabetic and lipid-lowering properties. The formulation was administered orally to Alloxan-induced diabetic Wistar rats over a specified treatment period. Various parameters including fasting blood glucose levels, body weight, serum lipid profile (total cholesterol, triglycerides, HDL, LDL, VLDL), and glycated hemoglobin (HbA1c) were evaluated to assess the therapeutic efficacy.
The results demonstrated a significant reduction in fasting blood glucose and HbA1c levels, along with an improvement in lipid profile, indicating potent antidiabetic and antihyperlipidemic activities of the polyherbal formulation.
This study suggests that the formulated polyherbal combination exhibits synergistic action and holds promise as an effective and natural alternative for the management of diabetes and its complications.},
        keywords = {Polyherbal formulation, Alloxan, Antidiabetic, Hypolipedimic.},
        month = {August},
        }