ANTI-MICROBIAL STUDY OF CENTELLA ASIATICA EXTRACT AGAINST PATHOGENIC BACTERIA

  • Unique Paper ID: 184784
  • PageNo: 46-68
  • Abstract:
  • Gotu kola, or Centella asiatica, is a traditional medicinal herb that has strong anti-bacterial properties among other pharmacological benefits. Assessing the anti-bacterial activity of the C. asiatica leaf extract against a variety of pathogenic microorganisms, including Candida albicans, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli, was the aim of this investigation. Centella asiatica leaves were macerated in a 90% hydroalcoholic solution for the leaf extraction procedure. The extract was then subjected to a phytochemical examination, and the agar well diffusion method was used to assess the extract's anti-bacterial efficacy. Proteins, triterpenoids, and flavonoids were among the bioactive substances found throughout the screening. For every pathogen examined, the extract showed notable inhibitory zones; the effects varied according to the extract concentration. In contrast to the common antibiotic chloramphenicol, Centella asiatica exhibited broad-spectrum anti-bacterial efficacy against B. subtilis and S. aureus. The study's findings supported the traditional use of Centella asiatica and opened up new possibilities for therapeutic research by indicating that it would be worthwhile to investigate for possible application as a natural anti-bacterial agent.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{184784,
        author = {DEBABRATA ROUTH and INDRANIL CHATTERJEE and SUCHETAN SARKAR and SOURAV DAS and MD. MIKAIL AZAM and ASHUTOSH KARMAKAR},
        title = {ANTI-MICROBIAL STUDY OF CENTELLA ASIATICA EXTRACT AGAINST PATHOGENIC BACTERIA},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {5},
        pages = {46-68},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=184784},
        abstract = {Gotu kola, or Centella asiatica, is a traditional medicinal herb that has strong anti-bacterial properties among other pharmacological benefits. Assessing the anti-bacterial activity of the C. asiatica leaf extract against a variety of pathogenic microorganisms, including Candida albicans, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli, was the aim of this investigation. Centella asiatica leaves were macerated in a 90% hydroalcoholic solution for the leaf extraction procedure. The extract was then subjected to a phytochemical examination, and the agar well diffusion method was used to assess the extract's anti-bacterial efficacy. Proteins, triterpenoids, and flavonoids were among the bioactive substances found throughout the screening. For every pathogen examined, the extract showed notable inhibitory zones; the effects varied according to the extract concentration. In contrast to the common antibiotic chloramphenicol, Centella asiatica exhibited broad-spectrum anti-bacterial efficacy against B. subtilis and S. aureus. The study's findings supported the traditional use of Centella asiatica and opened up new possibilities for therapeutic research by indicating that it would be worthwhile to investigate for possible application as a natural anti-bacterial agent.},
        keywords = {Centella asiatica, Anti-microbial activity, Pathogenic bacteria, Phytochemicals, Agar well diffusion, Herbal medicine},
        month = {September},
        }

Cite This Article

ROUTH, D., & CHATTERJEE, I., & SARKAR, S., & DAS, S., & AZAM, M. M., & KARMAKAR, A. (2025). ANTI-MICROBIAL STUDY OF CENTELLA ASIATICA EXTRACT AGAINST PATHOGENIC BACTERIA. International Journal of Innovative Research in Technology (IJIRT), 12(5), 46–68.

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