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@article{185703,
author = {Dr. Raja Shekar Perusomula and Ramesh Alluri and Gayathri Paturi and Lagde Nitin Balasaheb and Arghadeep Sarkar},
title = {MUTATION AND MUTAGENIC REASONS CONTRIBUTING TO PARKINSON'S DISEASE DEVELOPMENT},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {5},
pages = {2717-2724},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=185703},
abstract = {Parkinson's disease (PD) might be a energetic neurodegenerative clutter characterized by motor and non-motor side impacts that through and through debilitate the quality of life.is multifactorial, including both hereditary and natural variables. Later propels have uncovered an perplexing organize of transformations in a few qualities and the impact of natural mutagens that collectively contribute to dopaminergic neuron degeneration and degradationwithin the substantia nigra. This review investigates the mutational scene and mutagenic variables involved in PD, emphasizing atomic instruments, later discoveries, and their suggestions for future restorative techniques.},
keywords = {Parkinson's disease; genetic mutations; SNCA; alpha-synuclein; transcriptional mutagenesis; 8-oxodG; oxidative stress.},
month = {December},
}
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