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@article{186318,
author = {Payal Subhash Ghode and Reshma Dilip Pawar and Sunil Baban Rathod and Anjali Gahininath Kekan and Shilpa Balu Rohile},
title = {Ayurvedic Formulations with Potential Anticancer Activity: A Comprehensive Review of Traditional Wisdom and Modern Scientific Validation},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {6},
pages = {1125-1137},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=186318},
abstract = {Cancer remains one of the most significant global health challenges, driving the pursuit of effective and less toxic therapeutic options. Ayurveda, the ancient Indian system of medicine, offers a rich repository of plant-based formulations that have long been employed for various ailments, including tumors. This review aims to bridge traditional Ayurvedic knowledge with contemporary scientific evidence, highlighting formulations that exhibit promising anticancer activity. Key classical preparations such as Triphala, Ashwagandha (Withania somnifera), Guduchi (Tinospora cordifolia), and Curcuma longa have been documented for their antiproliferative, pro-apoptotic, anti-inflammatory, and immunomodulatory effects. Modern pharmacological investigations and preclinical studies provide growing support for these traditional claims, while ongoing clinical trials continue to clarify their therapeutic potential and safety profiles. By integrating ethnopharmacological insights with molecular and cellular research, this review underscores the value of Ayurvedic formulations as complementary or adjunct approaches to conventional cancer therapy. Further standardized studies, rigorous clinical validation, and quality control measures are essential to translate this traditional wisdom into evidence-based anticancer interventions.},
keywords = {Ayurveda; anticancer activity; herbal formulations; traditional medicine; Triphala; Ashwagandha; Guduchi; Curcuma longa; phytochemicals; apoptosis; immunomodulation; ethnopharmacology; complementary therapy; cancer therapeutics; integrative oncology},
month = {November},
}
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