THERMOGRAVIMETRIC ANALYSIS AND BIOLOGICAL EVALUATION OF 1, 3, 5 TRIZINES DERIVATIVES WITH SUBSTITUTUED AMINES

  • Unique Paper ID: 187083
  • PageNo: 7585-7594
  • Abstract:
  • The present study focuses on the thermogravimetric analysis (TGA) and biological evaluation of newly synthesized 1,3,5-triazine derivatives with substituted amines. The synthesized compounds were characterized using various physicochemical and spectral techniques to confirm their molecular structures. Thermogravimetric analysis was employed to determine the thermal stability and decomposition patterns of the triazine derivatives, revealing multi-step degradation processes with high thermal resistance, indicating their potential stability for pharmaceutical and material applications. In addition, the synthesized triazine derivatives were subjected to biological screening, including antibacterial, antifungal, antiviral assays. The results demonstrated that several derivatives exhibited significant biological activity, comparable to standard reference drugs. The variation in activity among the derivatives was attributed to the nature and position of the substituent amine groups on the triazine ring.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{187083,
        author = {GOPALKRUSHNA H. MURHEKAR and MADHURI G. KUKALKAR},
        title = {THERMOGRAVIMETRIC ANALYSIS AND BIOLOGICAL EVALUATION OF 1, 3, 5 TRIZINES DERIVATIVES WITH SUBSTITUTUED AMINES},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {7585-7594},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187083},
        abstract = {The present study focuses on the thermogravimetric analysis (TGA) and biological evaluation of newly synthesized 1,3,5-triazine derivatives with substituted amines. The synthesized compounds were characterized using various physicochemical and spectral techniques to confirm their molecular structures. Thermogravimetric analysis was employed to determine the thermal stability and decomposition patterns of the triazine derivatives, revealing multi-step degradation processes with high thermal resistance, indicating their potential stability for pharmaceutical and material applications. In addition, the synthesized triazine derivatives were subjected to biological screening, including antibacterial, antifungal, antiviral assays. The results demonstrated that several derivatives exhibited significant biological activity, comparable to standard reference drugs. The variation in activity among the derivatives was attributed to the nature and position of the substituent amine groups on the triazine ring.},
        keywords = {1,3,5-triazine, substituted amines, antibacterial, antifungal, antiviral assays},
        month = {December},
        }

Cite This Article

MURHEKAR, G. H., & KUKALKAR, M. G. (2025). THERMOGRAVIMETRIC ANALYSIS AND BIOLOGICAL EVALUATION OF 1, 3, 5 TRIZINES DERIVATIVES WITH SUBSTITUTUED AMINES. International Journal of Innovative Research in Technology (IJIRT), 12(6), 7585–7594.

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