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@article{187400,
        author = {Soumya Suneriya and Dr. Ramakant Sharma},
        title = {Effect of Gut Microbiota on Antidepressant Drugs},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {4302-4305},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187400},
        abstract = {The gut microbiota plays a crucial role in maintaining overall health, with emerging evidence suggesting its involvement in various psychiatric conditions, including depression. Recent studies have identified significant interactions between gut microbiota composition and the efficacy of antidepressant drugs, indicating that the gut-brain axis could be a key factor in modulating the therapeutic response to these medications. This review explores the latest findings on how gut microbiota influences the pharmacodynamics and pharmacokinetics of antidepressants, focusing on the potential mechanisms underlying these interactions. Furthermore, it evaluates the role of probiotics and prebiotics as adjunctive therapies for improving antidepressant efficacy and reducing side effects.},
        keywords = {Gut Microbiota, Depression, Selective Serotonin Reuptake Inhibitors, Dysbiosis, Neurotransmitter},
        month = {November},
        }