Recent Advances in Pharmacology: integrating RNA therapeutics, targeted modalities, nano-delivery, artificial intelligence and pharmacogenomics

  • Unique Paper ID: 187567
  • Volume: 12
  • Issue: 8
  • PageNo: 5605-5609
  • Abstract:
  • Pharmacology is experiencing an era of accelerated innovation, driven by the clinical success of nucleic-acid therapeutics, refinement of targeted modalities such as antibody–drug conjugates (ADCs), breakthroughs in nanodelivery systems, and the rapid incorporation of artificial intelligence (AI) into drug discovery. Coupled with expanding pharmacogenomic knowledge, these advances are moving therapeutics from empirical dosing toward mechanism-informed, personalized strategies. This review synthesizes the latest developments (2023–2025) across these domains, examines translational successes and persistent barriers (delivery specificity, PK/PD complexity, manufacturing, data bias, regulatory adaptation), and proposes integrative pathways to accelerate safe, equitable clinical implementation.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{187567,
        author = {Rajat Kumar Saini and Priyanka Bisht and Sanjay Kumar Verma and Sunil Kumar},
        title = {Recent Advances in Pharmacology: integrating RNA therapeutics, targeted modalities, nano-delivery, artificial intelligence and pharmacogenomics},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {5605-5609},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187567},
        abstract = {Pharmacology is experiencing an era of accelerated innovation, driven by the clinical success of nucleic-acid therapeutics, refinement of targeted modalities such as antibody–drug conjugates (ADCs), breakthroughs in nanodelivery systems, and the rapid incorporation of artificial intelligence (AI) into drug discovery. Coupled with expanding pharmacogenomic knowledge, these advances are moving therapeutics from empirical dosing toward mechanism-informed, personalized strategies. This review synthesizes the latest developments (2023–2025) across these domains, examines translational successes and persistent barriers (delivery specificity, PK/PD complexity, manufacturing, data bias, regulatory adaptation), and proposes integrative pathways to accelerate safe, equitable clinical implementation.},
        keywords = {RNA therapeutics; antibody–drug conjugates; nanocarriers; lipid nanoparticles; artificial intelligence; pharmacogenomics; precision medicine},
        month = {January},
        }

Cite This Article

Saini, R. K., & Bisht, P., & Verma, S. K., & Kumar, S. (2026). Recent Advances in Pharmacology: integrating RNA therapeutics, targeted modalities, nano-delivery, artificial intelligence and pharmacogenomics. International Journal of Innovative Research in Technology (IJIRT), 12(8), 5605–5609.

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