Isolation and Screening of Phenolic Antioxidants from Marine Fungi: A Review of Methodology and Therapeutic Potential

  • Unique Paper ID: 187639
  • Volume: 12
  • Issue: 6
  • PageNo: 5664-5666
  • Abstract:
  • Phenolic compounds are a major class of natural products recognized for their potent antioxidant activity, which is crucial for mitigating oxidative stress implicated in chronic diseases. Marine fungi, inhabiting extreme and competitive environments, represent a prolific yet largely untapped source of novel bioactive molecules. This review examines the current state-of-the art methodologies employed for the isolation, extraction, and invitro screening of phenolic antioxidants derived from marine fungal strains. We discuss established and emerging cultivation techniques that enhance phenolic production, detail advanced chromatographic and spectroscopic methods (HPLC-DAD, LC-MS/MS) for structural identification, and evaluate their liability of common antioxidant assays (DPPH,ABTS,FRAP). Finally, we highlight the significant therapeutic potential and critical future directions necessary to translate these marine-derived metabolites into viable nutraceuticals and pharmaceuticals.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{187639,
        author = {Chinthala sri Sravani},
        title = {Isolation and Screening of Phenolic Antioxidants from Marine Fungi: A Review of Methodology and Therapeutic Potential},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {5664-5666},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187639},
        abstract = {Phenolic compounds are a major class of natural products recognized for their potent antioxidant activity, which is crucial for mitigating oxidative stress implicated in chronic diseases. Marine fungi, inhabiting extreme and competitive environments, represent a prolific yet largely untapped source of novel bioactive molecules. This review examines the current state-of-the art methodologies employed for the isolation, extraction, and invitro screening of phenolic antioxidants derived from marine fungal strains. We discuss established and emerging cultivation techniques that enhance phenolic production, detail advanced chromatographic and spectroscopic methods (HPLC-DAD, LC-MS/MS) for structural identification, and evaluate their liability of common antioxidant assays (DPPH,ABTS,FRAP). Finally, we highlight the significant therapeutic potential and critical future directions necessary to translate these marine-derived metabolites into viable nutraceuticals and pharmaceuticals.},
        keywords = {},
        month = {November},
        }

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