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@article{189514,
        author = {Dahale Yashanjali and Bawane Sakshi and Darade Shraddha and Darade Krushna and Borude Abhishek and Patil Pragati and Chavhan Shankar and Dr. Gangurde Hemant H},
        title = {A REVIEW ON: A SMART HERBAL NANOTINCTURE: A POLYHERBAL NANO – HERBOSOMES APPROACH FOR TARGETED DERMATOLOGICAL THERAPY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {6724-6740},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189514},
        abstract = {Herbal medicines have long been employed in dermatological therapy owing to their broad pharmacological activities, favorable safety profile, and patient acceptability. However, the clinical translation of conventional herbal formulations is often limited by poor skin penetration, low bioavailability, instability of phytoconstituents, and lack of site-specific targeting. Recent advances in nanotechnology have opened new avenues for overcoming these challenges through the development of smart nano-delivery systems. Among them, polyherbal nano-herbosomes, formulated as herbal nanotinctures, have emerged as a promising strategy for targeted dermatological applications.
Nano-herbosomes are lipid-based vesicular systems in which bioactive phytoconstituents are complexed with phospholipids, resulting in enhanced physicochemical stability, improved skin permeation, and controlled release behavior. The integration of multiple herbal extracts in a polyherbal nano-herbosomal system enables synergistic therapeutic effects, addressing multifactorial skin disorders such as acne, psoriasis, eczema, wound infections, hyperpigmentation, and inflammatory dermatoses. Furthermore, smart nanotincture formulations offer advantages such as ease of application, improved patient compliance, enhanced transdermal absorption, and reduced systemic toxicity.
This review comprehensively discusses the concept, formulation strategies, preparation methods, characterization techniques, and mechanism of action of polyherbal nano-herbosomes for dermatological therapy. It also highlights recent research advances, therapeutic applications, safety considerations, regulatory perspectives, and future prospects of smart herbal nanotinctures in targeted skin delivery. The review emphasizes the potential of nano-herbosomal technology as a transformative approach in modern herbal dermatology, bridging traditional medicine with advanced nanopharmaceutical systems.},
        keywords = {Smart herbal Nanotincture, Nano-herbosomes, Targeted dermatological therapy, Skin targeting.},
        month = {December},
        }