COMPREHENSIVE LITERATURE REVIEW ON TUBERCULOSIS: EPIDEMIOLOGY, PATHOPHYSIOLOGY, DIAGNOSIS, TREATMENT, AND CONTROL STRATEGIES

  • Unique Paper ID: 189619
  • Volume: 12
  • Issue: 7
  • PageNo: 6896-6906
  • Abstract:
  • Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a leading infectious cause of mortality globally, affecting millions of individuals annually. This comprehensive literature review examines current evidence on TB epidemiology, pathophysiology, diagnostic approaches, treatment strategies, drug resistance patterns, and control measures. A systematic search identified numerous relevant publications covering various aspects of TB prevention, management, and elimination. The review synthesizes findings on TB burden, transmission mechanisms, clinical manifestations, diagnostic modalities including both conventional and molecular approaches, first-line and drug-resistant TB treatment regimens, and public health strategies. Key challenges including multidrug resistance (MDR-TB), extensively drug-resistant TB (XDR-TB), TB-HIV coinfection, and TB in vulnerable populations are addressed. Novel therapeutic approaches and diagnostic tools are also discussed. This review provides a comprehensive overview of contemporary TB knowledge to inform clinical practice and public health policy.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{189619,
        author = {Sakshi Bagul and Kavita. T. Daware},
        title = {COMPREHENSIVE LITERATURE REVIEW ON TUBERCULOSIS: EPIDEMIOLOGY, PATHOPHYSIOLOGY, DIAGNOSIS, TREATMENT, AND CONTROL STRATEGIES},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {6896-6906},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189619},
        abstract = {Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a leading infectious cause of mortality globally, affecting millions of individuals annually. This comprehensive literature review examines current evidence on TB epidemiology, pathophysiology, diagnostic approaches, treatment strategies, drug resistance patterns, and control measures. A systematic search identified numerous relevant publications covering various aspects of TB prevention, management, and elimination. The review synthesizes findings on TB burden, transmission mechanisms, clinical manifestations, diagnostic modalities including both conventional and molecular approaches, first-line and drug-resistant TB treatment regimens, and public health strategies. Key challenges including multidrug resistance (MDR-TB), extensively drug-resistant TB (XDR-TB), TB-HIV coinfection, and TB in vulnerable populations are addressed. Novel therapeutic approaches and diagnostic tools are also discussed. This review provides a comprehensive overview of contemporary TB knowledge to inform clinical practice and public health policy.},
        keywords = {Tuberculosis, Mycobacterium tuberculosis, drug resistance, diagnosis, treatment, control strategies, epidemiology},
        month = {December},
        }

Cite This Article

Bagul, S., & Daware, K. T. (2025). COMPREHENSIVE LITERATURE REVIEW ON TUBERCULOSIS: EPIDEMIOLOGY, PATHOPHYSIOLOGY, DIAGNOSIS, TREATMENT, AND CONTROL STRATEGIES. International Journal of Innovative Research in Technology (IJIRT), 12(7), 6896–6906.

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