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@article{189765,
        author = {Tiyasha Mishra and Ahana Chakraborty and Priyanka Jana and Shatavisa Patra},
        title = {Identification of Novel genes responsible for the pathogenesis of Endometriosis: An In-Silico approach},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {332-347},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189765},
        abstract = {Among all the Female gynaecological disorders, Endometriosis is one of the most debilitating conditions which presents with severe abdominal pain, dysmenorrhea, vomiting and is a powerful stepping stone towards Infertility. It is an Immune-Reproductive disorder, fostered by massive immune infiltration, various genetic alterations, diet and environmental perturbations, and impaired gene regulation. The study revolves around deduction of novel genes that are responsible for the underlying condition and hence prove to be a diagnostic marker. Five genes, namely- DCN, EGFR, MET, FN1 and HSPA4 have been identified after relentless exploration of publicly available GEO datasets. Functional annotation of the genes is suggestive of their contribution towards several factors that are suitable for the progression of endometriosis. In future, these genes can be targeted using novel drugs through high throughput screening of libraries and provide a therapeutic edge to the study. SNP analyses can be conducted to find out the deleterious polymorphisms in these genes leading to disease progression.},
        keywords = {Endometriosis, Therapeutic, GEO, genes, novel.},
        month = {January},
        }