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@article{189771,
        author = {Girish Manik Gore and Anuradha Santosh Salunke and Maaz Aaquil and Namrata Shyam Jadhav and Amol Rohidas Jadhav},
        title = {ORODISPERSIBLE TABLETS: PATIENT FRIENDLY FORMULATIONS IN PEDIATRICS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {789-816},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189771},
        abstract = {The development of patient-friendly dosage forms has become a growing priority in pediatric pharmacotherapy due to challenges associated with swallowing conventional tablets and capsules. Orodispersible tablets (ODTs), also known as fast-dissolving or melt-in-mouth tablets, have emerged as an effective solution to enhance compliance, safety, and therapeutic efficacy in children. These formulations disintegrate rapidly in the oral cavity without water, offering advantages for pediatric, geriatric, and dysphagic patients.
Simultaneously, herbal medicine continues to play a vital role in pediatric healthcare, particularly when synthetic drugs pose higher risks of adverse effects. However, poor solubility, stability, and low bioavailability of herbal bioactives often limit their effectiveness. Nanotechnology-based delivery systems—such as nanoemulsions, liposomes, solid lipid nanoparticles, and nanocrystals—offer promising solutions by improving the solubility and absorption of phytoconstituents. Incorporating such nano-herbal systems into ODTs can further enhance patient compliance and therapeutic outcomes.
Despite these advancements, challenges remain in optimizing formulation methods, ensuring stability, achieving dose uniformity, and addressing regulatory concerns. Future directions include the integration of personalized medicine, microbiome-based therapies, and smart packaging technologies. The convergence of nanotechnology and herbal ODTs represents a promising frontier in developing safe, effective, and patient-friendly formulations for pediatric use.},
        keywords = {Orodispersible tablets, Pediatrics, Herbal medicine, Nanotechnology, Bioavailability, Pediatric drug delivery},
        month = {January},
        }