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@article{189900,
        author = {M.Alekhya and M.Madhu and U.Narasimhulu and K.ThippeshBabu and S.MahammedHussain and S.Charitha Priyadarshini and T.Vinodkumar},
        title = {The Role of Natural Products in Kidney Protection: A Review of Recent Pharmacological Findings},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {396-409},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189900},
        abstract = {Natural products have emerged as promising agents for kidney protection, offering diverse therapeutic benefits through their unique biological activities and chemical structures. This review explores the role of natural products in promoting renal health, focusing on recent pharmacological findings. The growing interest in natural products for kidney health is driven by factors such as the limitations of current pharmaceutical treatments, the potential for fewer side effects, and the increasing global prevalence of kidney disease. Various natural products, including herbal extracts, phytochemicals, marine-derived compounds, mushroom extracts, and essential oils, have demonstrated nephroprotective effects through multiple mechanisms of action. These mechanisms include antioxidant properties, anti-inflammatory effects, blood pressure regulation, glucose metabolism modulation, fibrosis inhibition, and oxidative stress reduction. Specific natural products, such as Anacyclus pyrethrum, phytovesicularnanoconstructs, and bioactive compounds with diuretic effects, have shown promising results in preclinical studies. 
	Clinical investigations have also yielded encouraging outcomes regarding the efficacy and safety of natural substances for renal protection in human studies. However, challenges and limitations, such as the need for standardized dosing, long-term safety assessments, and a comprehensive understanding of interactions and mechanisms, must be addressed to ensure the effective integration of natural products into kidney disease management. Future research directions include the development of innovative drug delivery systems, regenerative therapies, and advanced disease modeling techniques, as well as integrating natural products into conventional kidney treatments to improve therapeutic outcomes. This review serves as a foundation for further research and the application of natural products in promoting renal health and managing kidney diseases.},
        keywords = {Natural products, Kidney protection, Nephroprotective effects, Herbal extractsPhytochemicals, Antioxidant properties},
        month = {January},
        }