Formulation and Evaluation of Herbal Nanogel for Topical Application: A Research Study

  • Unique Paper ID: 190178
  • Volume: 12
  • Issue: 8
  • PageNo: 3226-3235
  • Abstract:
  • Nanotechnology-based formulations such as nanogels have attracted significant attention because of their superior physicochemical properties, including enhanced penetration, controlled release, biocompatibility, and high drug-loading capacity. The present research focuses on formulating an herbal nanogel incorporating plant-based active constituents using Carbopol 940 as the polymeric base. The prepared nanogel was characterized for organoleptic properties, homogeneity, pH, spreadability, viscosity, drug content, in-vitro drug release, antimicrobial activity, and stability. Results confirmed that the nanogel exhibited favourable dermatological pH (5.5–6.5), smooth texture, uniform drug distribution, good spreadability, sustained drug release, and adequate stability under accelerated conditions. These outcomes indicate that herbal nanogels can serve as promising alternatives to conventional topical formulations for treating skin conditions.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{190178,
        author = {Mahesh D Bhalsing and Ganesh N Kardile and Vaibhav B Sagade},
        title = {Formulation and Evaluation of Herbal Nanogel for Topical Application: A Research Study},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {3226-3235},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190178},
        abstract = {Nanotechnology-based formulations such as nanogels have attracted significant attention because of their superior physicochemical properties, including enhanced penetration, controlled release, biocompatibility, and high drug-loading capacity. The present research focuses on formulating an herbal nanogel incorporating plant-based active constituents using Carbopol 940 as the polymeric base. The prepared nanogel was characterized for organoleptic properties, homogeneity, pH, spreadability, viscosity, drug content, in-vitro drug release, antimicrobial activity, and stability. Results confirmed that the nanogel exhibited favourable dermatological pH (5.5–6.5), smooth texture, uniform drug distribution, good spreadability, sustained drug release, and adequate stability under accelerated conditions. These outcomes indicate that herbal nanogels can serve as promising alternatives to conventional topical formulations for treating skin conditions.},
        keywords = {Aloe Vera, Anti-inflammatory, Boswellia serrate, Curcumin, Herbal Formulation, Nanogel, Wound Healing.},
        month = {January},
        }

Cite This Article

Bhalsing, M. D., & Kardile, G. N., & Sagade, V. B. (2026). Formulation and Evaluation of Herbal Nanogel for Topical Application: A Research Study. International Journal of Innovative Research in Technology (IJIRT), 12(8), 3226–3235.

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