Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{190473,
        author = {Desai Khushi and Meera Devi Mazhavancheril and Dr.M.N.Noolvi},
        title = {A Review on Analytical methods for the Simultaneous Estimation of Aceclofenac, Paracetamol and Serratiopeptidase in bulk and combined dosage forms},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {4193-4201},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190473},
        abstract = {The simultaneous estimation of Aceclofenac, Paracetamol, and Serratiopeptidase in bulk and combined dosage forms has gained significant importance due to their widespread use in the management of pain and inflammation. Numerous analytical methods have been developed to ensure accurate, precise, and reproducible quantification of these drugs in multicomponent formulations. This review summarizes various analytical techniques including UV-visible spectrophotometry, Reversed-phase High-Performance Liquid Chromatography (RP-HPLC), High-Performance Thin-Layer Chromatography (HPTLC) and stability-indicating methods reported for the combined analysis of these three drugs. The article highlights method development strategies, selection of wavelengths, mobile phases, chromatographic conditions, validation parameters and the advantages and limitations of each method. Special emphasis is placed on sensitivity, specificity, linearity, range and robustness as per ICH guidelines. This review aims to provide comprehensive insights into existing analytical approaches that can support routine quality control and research applications for Aceclofenac, Paracetamol, and Serratiopeptidase in Pharmaceutical formulations.},
        keywords = {Aceclofenac, Paracetamol, Serratiopeptidase, UV Spectrophotometry, RP-HPLC, HPTLC.},
        month = {January},
        }