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@article{190486,
        author = {A.SELVI and NIVETHA.B},
        title = {Formulation and evaluation of CASSIA ALATA containing ANTIFUNGAL SPRAY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {8},
        pages = {994-1000},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190486},
        abstract = {Cassia alata, a medicinal plant widely recognized for its potent antifungal properties, has been traditionally employed in the treatment of various skin infections. The present study focuses on the formulation and evaluation of a topical antifungal spray incorporating Cassia alata extract as the active ingredient. The spray was designed as a film-forming system to enhance drug contact time, permeability, and sustained release at the site of infection. Key formulation parameters such as polymer concentration, solvent system, nozzle type, and spray ability were optimized to achieve uniform distribution and effective drug delivery. The prepared spray was subjected to physicochemical evaluation, including viscosity, pH, drying time, and film-forming ability, along with in vitro antifungal activity against common dermatophytes. Results demonstrated that the Cassia alata-based spray exhibited significant antifungal efficacy, improved bioavailability, and reduced irritation compared to conventional topical preparations. The film-forming nature of the spray provided continuous drug release and accelerated wound healing through moisture control.},
        keywords = {Cassia alata; anti-fungal; topical formulation.},
        month = {December},
        }